Seroepidemiology of Human Enterovirus 71, Singapore
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چکیده
Human enterovirus 71 has caused outbreaks in many parts of the world, especially Southeast Asia, with some fatal cases. The epidemiology of this viral infection is not well understood. We conducted a serologic survey in Singapore children, and the results indicate that infection occurs largely in preschool settings.
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Author's response to reviews Title: The changing seroepidemiology of enterovirus 71 infection among children and adolescents in Singapore Authors:
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The changing seroepidemiology of enterovirus 71 infection among children and adolescents in Singapore
BACKGROUND Enterovirus 71 (EV71) has caused recurrent epidemics of hand, foot and mouth disease among children in Singapore. Between August 2008 and July 2010, we conducted a survey to estimate the seroprevalence of EV71 infection among children and adolescents aged 1-17 years. We compared our EV71 seroepidemiologic findings with a previous study conducted in 1996-1997. METHODS The survey inv...
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